PcrV immunization enhances survival of burned Pseudomonas aeruginosa-infected mice.
نویسندگان
چکیده
Burned Pseudomonas aeruginosa-infected mice immunized against PcrV, a type III virulence system translocating protein, showed significantly enhanced survival compared to controls. Survival was non-O serotype specific and correlated with a reduced systemic microbial load. Infection with a high-level toxin A-producing strain required supplemental antitoxin treatment to enhance survival.
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عنوان ژورنال:
- Infection and immunity
دوره 69 9 شماره
صفحات -
تاریخ انتشار 2001